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The antibody to NGF (AbNGF) was administered 1 h before ozone exposure (A, i and ii) or 2 days before ozone exposure (A, iii). Physiological measurements were made either 1 or 3 days after ozone exposure. To test the role of neurokinin receptors in ozone-induced airway hyperreactivity, neurokinin receptor antagonists were administered during physiological measurements 1, 2, or 3 days after ozone exposure (B).
