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Relative expression level (by qRT-PCR) of renin-angiotensin system (RAS) components in the kidney of Bbs2−/−, Bbs4−/− mice, and WT controls. Relative mRNA level of angiotensinogen (AGT; A), renin (B), angiotensin-converting enzyme (ACE; C), ACEII (D), angiotensin receptor type 1a (AT1a; E), and AT1b (F) in the kidney of Bbs2−/− and Bbs4−/− mice compared with control littermates. *P < 0.05 compared with WT mice; n = 3–6 per group.
