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. 2010 Nov 12;300(2):H652–H663. doi: 10.1152/ajpheart.00859.2010

Fig. 8.

Fig. 8.

Effects of TTX (100 nM and 1 μM) and lidocaine (2%) applied to the pool surrounding the dorsal roots on the compound action potential evoked by single-pulse electrical stimulation of the tibial nerve in 5 rats whose femoral artery was ligated 72 h before the start of the experiment. A: recording of the compound action potential recorded from a filament of the L4 dorsal root. Note that both TTX (1 μM) and lidocaine abolished the compound action potential arising from the stimulation of group III and IV afferents in this particular instance. B: summary data from 5 rats in which the effects of TTX and lidocaine on the compound action potential (CAP) are expressed as a percentage of the control area. †A significant decrease (P < 0.05) in area of the CAP from control values.