Fig. 1.

Continuous measurement of mean arterial pressure (MAP) in wild-type (WT) and large-conductance Ca²⁺-activated K⁺ channel (BK) β₁-knockout (KO) mice for 7 days after telemetry implantation. MAP was sampled for 10 s every 10 min. A: daily MAP calculated as the average of 24 hourly measurements. B: hourly MAP calculated as the average of 6 measurements each hour at day 6 and day 7. C: averaged MAP at night (6:00 P.M.-6:00 A.M.) and during the day (6:00 A.M.-6:00 P.M.). D: daily heart rate (HR) in WT and BK β₁-KO mice measured for 7 days after telemetry implantation. HR was sampled for 10 s every 10 min. Daily HR was calculated as the average of 24 hourly measurements. *Significantly different from WT mice (P < 0.05).