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Comparison of contractile and dilatory responses in WT and BK β1-KO MA in vitro. A and B: concentration-response curves of NE and KCl in WT and BK β1-KO MA. C: contractile responses to KCl (40 mmol/l) with or without pretreatment of paxilline (0.5 μmol/l). D: concentration-responses curves of isoproterenol (ISP) in PE (1 μmol/l)-precontracted WT and BK β1-KO MA with or without ICI-118551 (1 μmol/l) pretreatment. *Significantly different from WT MA.
