Table 4.
cMyBP-C p.A31P genotype | P-value | ||
---|---|---|---|
Heterozygous (G/C) | Wild type (G/G) | ||
n, gender distribution | 14 (4 males) | 34 (14 males) | - |
Age, y (median, 95% range) | 5.7, 4.0; 9.0 | 4.5, 4.0; 6.0 | 0.17 |
Weight, kg (median, 95% range) | 6.0, 4.5; 8.8 | 5.1, 8.7; 3.5 | > 0.05 |
IVSd, mm (median, 95% range) | 3.7, 3.1; 6.2 | 3.9, 2.9; 6.2 | 0.40 |
LVIDd, mm (median, 95% range) | 16.6, 13.8; 19.3 | 15.9, 13.8; 1.9 | 0.20 |
LVFWd, mm (median, 95% range) | 4.0, 2.7; 7.2 | 4.0, 2.9; 5.8 | 0.70 |
IVSs, mm (median, 95% range) | 6.6, 5.0; 12.4 | 6.7, 5.0; 9.0 | 0.82 |
LVIDs, mm (median, 95% range) | 9.6, 3.9; 12.9 | 10.0, 6.3; 14.0 | 0.83 |
LVFWs, mm (median, 95% range) | 7.0, 5.2; 9.2 | 7.0, 4.1; 9.8 | 0.08 |
LA/Ao, (median, 95% range) | 1.0, 0.9; 1.3 | 1.0, 0.9; 1.4 | 0.06 |
% with murmur | 7 | 0 | |
% with SAM | 7 | 0 | |
% with obliteration | 14 | 3 | |
% with hypertrophic papillary muscle | 7 | 12 | |
% with increased LA | 0 | 0 |
IVSd: diastolic intraventricular septum, LVIDd: diastolic left ventricular inner diameter, LVFWd: diastolic left ventricular free wall, IVSs: systolic intraventricular septum, LVIDs: systolic left ventricular inner diameter, LVFWs: systolic left ventricular free wall, LA/Ao: left atrium over aorta.