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. 2011 Feb 23;6(2):e16999. doi: 10.1371/journal.pone.0016999

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Takigawa et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The edges (drug-target interactions) were colored according to R1 to R8, accompanying with 8 subnetworks, each being one of R1 to R8. The size of nodes indicates the size of degrees (or promiscuity).