Table 5.

Relevant pharmacogenetic association studies that focused on MAOA

Study	Gene	Drug	Results	Quality (0–31)	Sample size
Tzeng et al.150	MAOA	Mirtazapine	Long-form polymorphism ↓ response	15	58
Leuchter et al.133	MAOA	Placebo, various antidepressants	rs6323 G allele ↓ placebo response	15	132
Domschke et al.151	MAOA	Various antidepressants	In female alleles 3a, 4, 5 ↓ response	18	340
Tadic et al.154	MAOA	Mirtazapine, paroxetine	In female rs6323 T/T ↑ response to mirtazapine	15	102
Yu et al.148	MAOA	Fluoxetine	In female allele 3a ↑ response	14	230
Serretti et al.119	MAOA	Various	No association	22	185
Peters et al.85	MAOA	Fluoxetine	rs1465108G/A and rs6323A/C ↑ response	19	96
Yoshida et al.155	MAOA	Fluvoxamine	MAOA VNTR ↑ iatrogenic nausea	16	54
Cusin et al.153	MAOA	Fluvoxamine, paroxetine	No association	22	217
Yoshida et al.81	MAOA	Fluvoxamine	No association	15	66
Müller et al.152	MAOA	Moclobemide	No association	12	62

↑= positive association; ↓ = negative association; VNTR = variable number tandem repeat.