TABLE 2.

Histopathology of Lungs from Mice after Repeated Aspiration of SWCNTs, AB, or UFCB

Method	Lesion	Process	Severitya	Distribution	PBS	UFCB	AB	SWCNT
H&E	Histiocytosis		Moderate	Diffuse		6/6
	Inflammation		Minimal	Focal, subpleural	1/6
	Inflammation		Mild	Perivascular		3/6
	Inflammation	AM	Mild	Multifocal			2/6
	Inflammation	AM	Moderate	Multifocal			4/6
	Inflammation	Granuloma	Minimal	Focal		1/6
	Inflammation	Pyogranulomatous	Moderate	Multifocal				7/7
TB	Histiocytosis		Moderate	Diffuse		5/6
	Histiocytosis		Severe	Diffuse		1/6
	Inflammation		Minimal	Focal, subpleural	1/6
	Inflammation	AM	Mild	Multifocal			2/6
	Inflammation	AM	Moderate	Multifocal			4/6
	Inflammation	Pyogranulomatous	Moderate	Multifocal				7/7
	Fibrosis		Minimal			1/6	2/6
	Fibrosis		Mild				4/6	7/7

Note. TB, trichrome blue; H&E, hemostatin and eosin.

^aFor all endpoints, the process appeared to be chronic rather than acute as was active for the perivascular inflammation in the UFCB group.