Table 1.

Application of Functional Protein Microarrays in Large‐Scale Projects

Assay Type	Array Content	Type of Probe	No. of Probe	Application	Reference
Protein–peptide interaction	159 human SH2 and PTB domains	Peptide	61	Protein interaction network	74
Protein–DNA interaction	282 yeast TFs	DNA motif	75	Protein–DNA interaction network	65
	4191 human proteins	DNA motif	460	Protein–DNA interaction network	66
Kinase assay	Yeast proteome	Protein kinase	87	Phosphorylation network	54
Antigen–antibody interaction	196 human autoantigens	Autoimmune disease patient sera	>50	Antibody profiling	78
	82 coronavirus proteins	SARS patient sera	602	Antibody profiling	84
	E. coli proteome	IBD patient sera	134	Biomarker identification	81
	5005 human proteins	Ovarian cancer patient sera	60	Biomarker identification	80
	5011 human proteins	AIH patient sera	278	Biomarker identification	83

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