Table 4.

Statistical parameters of GH score validation for Hypo 1.

S. No	Parameters	Results
1	Total molecules in database (D)	453
2	Total no. of actives in database (A)	206
3	Total hits (Ht)	230
4	Active hits (Ha)	197
5	% Yield of actives [(Ha/Ht) X 100]	85.65
6	% Ratio of actives [(Ha/A) X 100]	95.63
7	Enrichment factor (E) [(Ha X D)/(Ht X A)]	1.88
8	False negatives [A - Ha]	9
9	False positives [Ht - Ha]	33
10	Goodness of hit (GH)*	0.76

*[(Ha/4HtA)(3A + Ht) X (1 – (Ht – Ha)/(D –A))]; GH score of 0.6-0.8 indicates a very good model.