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. Author manuscript; available in PMC: 2011 Feb 24.
Published in final edited form as: J Immunol. 2010 Mar 5;184(7):3850–3856. doi: 10.4049/jimmunol.0902935

FIGURE 6.

FIGURE 6

CD4 T cells maintain cytotoxic activity in the absence of IFN-γ. A, Experimental design of the in vivo cytotoxicity assay. IFN-γ neutralization was confirmed by ELISA. Forty hours after target cell transfer, recipient mice were sacrificed, and the percentage-specific lysis was calculated as described in Materials and Methods. B, Bar diagram showing the percentage of specific lysis after in vivo IFN-γ neutralization or isotype control treatment. C, Bar diagram shows the percentage of specific lysis of long-term infected IFN-γ−/− mice relative to long-term infected wild-type controls. Error bars represent SD.