FIGURE 4.
γHV68-specific memory CD8 T cells protect a γHV68 challenge. Sublethally irradiated B6.PL mice received 1 × 106 CFSE-labeled CD44+CD8+ T cells isolated from the spleens of B6 mice that have been infected with γHV68 for at least 3 mo (γHV68 memory; 
) or from noninfected age-matched controls (irrelevant memory; ■). The recipient B6.PL mice were rested for 30 days after adoptive cell transfer and subsequently infected with γHV68. The bar diagram shows the number of γHV68-infected cells in the spleen 14 days after infection. Bars represent the mean value of three experimental animals, and error bars indicate SEM. Similar results were obtained in two independent experiments.