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Contribution of T2544 to S. Typhi pathogenesis. (A) Kaplan-Meier plot of cumulative mortality after mice (n = 10 per group) were orally challenged with bacteria. (B) Competitive index (C.I.) analysis. Mice were infected orally with 1:1 mixture of Ty2 and Ty2Δt2544, and live bacteria were recovered from the blood and visceral organs. A representative of three independent experiments is shown here.
