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Representative Western blot analyses of 12/15-lipoxygenase expression (A) and (C) and 12/15-lipoxygenase protein contents (%) assessed by densitometry (B) and (D), in the sciatic nerve and spinal cord of control and diabetic mice maintained with or without PMI-5011 treatments. C, control; D, diabetic; T, PMI-5011 treatment; 12/15 LO, 12/15-lipoxygenase. Mean ± SEM, n=7-8 per group. *P<0.05 vs. the non-diabetic control group.
