Table I.
Variables | Control | Control with PMI-5011 |
Diabetic | Diabetic with PMI-5011 |
---|---|---|---|---|
Baseline (after induction of STZ-diabetes) | ||||
Body weight (g) | 24.5±0.5 | 24.1±0.6 | ||
Blood glucose (mmol/l) | 8.5±0.3 | 17.1±0.6a | ||
12-week time point (prior to interventions) | ||||
Body weight (g) | 37.3±0.7 | 38.8±0.9 | 29.1±0.3a | 29.6±0.3a |
Blood glucose (mmol/l) | 9.1±0.3 | 9.1±0.3 | 27.5±0.5a | 27.5±1.0a |
19-week time point (final measurements) | ||||
Body weight (g) | 39.2±0.8 | 39.6±1.0 | 29.1±0.4a | 29.1±0.3a |
Blood glucose (mmol/l) | 9.0±0.1 | 9.0±0.2 | 27.2±1.3a | 26.4±1.7a |
Data are expressed as mean ± SEM, n=18-20 per group.
P<0.01 vs. the non-diabetic controls.