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. Author manuscript; available in PMC: 2011 Dec 15.
Published in final edited form as: Bioorg Med Chem. 2010 Nov 9;18(24):8592–8599. doi: 10.1016/j.bmc.2010.10.018

Figure 2.

Figure 2

In vitro MeDAS staining (A and D) of myelin sheaths in corpus callosum in comparison with Black-Gold (B and E) and MBP staining (C and F) in adjacent sections. Arrows show myelinated corpus callosum. A-C, Plp-Akt-DD mouse brain sections stained with MeDAS, Black-Gold and MBP, respectively. D-F, Control mouse brain sections stained with MeDAS, Black-Gold and MBP, respectively. The corpus callosum region visualized by MeDAS appeared to be much larger in the Plp-Akt-DD mouse brain than in the control littermate wild-type mouse brain, which was the same pattern that was observed in the Black-Gold or MBP antibody staining.