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. Author manuscript; available in PMC: 2011 Feb 24.
Published in final edited form as: Stat Med. 2008 Dec 20;27(29):6158–6174. doi: 10.1002/sim.3434

Table 3.

Percent each covariate was selected, average percentage of correct associations and average percentage of incorrect associations of the 500 replicates of Simulated Disease 1 for each selection method

Covariate 95% CI Backward Forward Stepwise SSVS

p=0.01 p=0.05 p=0.20 p=0.01 p=0.05 p=0.20 p=0.01 p=0.05 p=0.20 w=0.25 w=0.5 w=0.5 or 0.25 informed β-prior means
Smoking+ 100 100 100 100 100 100 100 100 100 100 100 100 100 100
Alcohol+ 100 99.8 100 100 99.8 100 100 99.8 100 100 100 100 100 99.6
XPD+ 100 100 100 100 100 100 100 100 100 100 99.8 100 100 99.8
Fiber 7.4 4.8 11.6 10.2 5.0 11.4 10.2 4.4 11.4 10.2 0 0 0 0
Folate+ 100 100 100 100 100 100 100 100 100 100 100 100 100 100
MTHFR+ 97.6 87.0 96.2 97.6 84.0 95.0 97.4 83.4 95 97.4 89.2 95.4 93.6 87.2
X6 14.0 23.4 30.8 26.4 22.0 30.4 26.4 21.8 30.4 26.4 0 0 0 0
X7 5.2 1.2 5.2 5.6 1.2 5.0 5.6 1.2 5 27.8 0 0 0 0
X8 16.4 26.0 34.6 27.8 24.6 33.6 27.8 24.2 33.6 25.2 4.2 12.8 3.8 3.6
X9 14.8 22.6 29.8 25.0 22.4 30.2 25.2 22.4 30.2 25.2 0 0 0 0
X10 5.4 2.6 8.0 6.8 3.0 7.4 6.8 3.0 7.4 6.8 1.2 5.6 0.6 0.6
X15 5.4 1.0 6.0 5.6 1.5 5.6 5.6 1.0 5.6 5.6 3.0 13.2 2.8 2.8
Avg. correct Associations 94.1 92.1 89.2 90.9 92.0 89.3 90.8 92.1 89.3 89.2 98.4 97.0 98.9 98.3
Avg. incorrect associations 5.9 7.9 10.8 9.2 8.0 10.7 9.2 7.9 10.7 10.8 1.6 3.0 1.1 1.7
Avg. Ratio* 15.9 11.7 8.2 9.9 11.5 8.3 9.9 11.7 8.3 8.2 60.6 32.1 87.2 57.8
+

denotes covariate in true model

*

Avg. Ratio is calculated as the Avg. Correct Associations/Avg. Incorrect Associations