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. Author manuscript; available in PMC: 2011 Feb 24.
Published in final edited form as: Stat Med. 2008 Dec 20;27(29):6158–6174. doi: 10.1002/sim.3434

Table 4.

Percent each covariate was selected, average percentage of correct associations and average percentage of incorrect associations of the 500 replicates of Simulated Disease 2 for each selection method.

Covariate 95% CI Backward Forward Stepwise SSVS

p=0.01 p=0.05 p=0.20 p=0.01 p=0.05 p=0.20 p=0.01 p=0.05 p=0.20 w=0.25 w=0.5 w=0.5 or 0.25 informed β-prior means
Smoking+ 100 100 100 100 100 100 100 100 100 100 100 100 100 100
Alcohol+ 100 35.6 60.8 83.6 33.8 59.6 83.6 33.0 59.4 83.6 49.2 68.6 60.0 38.4
XPD+ 76.8 46.8 73.6 76.6 43.8 73.0 76.6 43.4 73.0 76.6 53.8 71.0 64.4 49.2
Fiber 10.4 5.0 13.4 11.4 5.2 13.2 21.4 4.6 13.2 11.4 0 0 0 6.8
Folate+ 100 100 100 100 100 100 100 100 100 100 100 100 100 100
MTHFR+ 89.0 74.2 90.8 89.0 73.8 90.4 89.2 73.4 90.4 89.2 68.4 86.4 83.2 63.2
X6+ 100 100 100 100 99.2 100 100 95.0 100 100 99.4 99.8 99.8 99.2
X7+ 100 100 100 100 100 100 100 100 100 100 100 100 100 100
X10+ 53.2 22.2 49.6 52.0 20.6 49.2 52.0 19.8 49.2 52.0 29.0 49.6 44.0 24.2
X11 42.4 38.8 53.6 47.6 36.8 53.2 47.6 36.4 53.0 47.6 0 0 0 0
X12 50.4 48.6 57.6 54.2 46.0 56.4 54.4 45.8 56.4 54.4 0 0 0 0
X13 46.8 43.0 58.4 53.0 42.4 58.2 53.0 41.6 58.2 53.0 0 0 0 0
X14 21.6 15.8 29.0 26.0 15.4 29.0 25.8 15.4 29.0 26.0 0 0 0 0
Avg. Correct Associations 80.6 71.4 74.0 77.6 71.2 74.0 76.8 70.8 74.0 77.6 84.6 90.4 88.6 82.1
Avg. Incorrect Associations 19.4 28.6 25.9 22.4 28.8 26.0 23.1 29.2 26.0 22.4 15.4 9.6 11.4 17.9
Avg. Ratio* 4.1 2.5 2.9 3.5 2.5 2.8 3.3 2.4 2.8 3.5 5.5 9.4 7.74 4.6
+

Denotes covariate in the true model

*

Avg. Ratio is calculated as the Avg. Correct Associations/Avg. Incorrect Associations.