Table 5.
Percent each covariate was selected, average percentage of correct associations and average percentage of incorrect associations of the 500 replicates of Simulated Disease 3 for each selection method
| Covariates | 95% CI | Backward | Forward | Stepwise | SSVS | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| p=0.01 | p=0.05 | p=0.20 | p=0.01 | p=0.05 | p=0.20 | p=0.01 | p=0.05 | p=0.20 | w=0.25 | w=0.5 | w=0.5 or 0.25 | informed β-prior means | ||
| Smoking+ | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 |
| Alcohol+ | 100 | 99.0 | 99.8 | 100 | 99.6 | 99.8 | 100 | 99.6 | 99.8 | 100 | 99.4 | 100 | 100 | 98.8 |
| XPD+ | 100 | 99.6 | 100 | 100 | 99.8 | 100 | 100 | 99.8 | 100 | 100 | 99.8 | 100 | 100 | 99.6 |
| Fiber | 25.0 | 25.6 | 43.0 | 42.4 | 5.2 | 12.0 | 13.0 | 4.8 | 12.0 | 13.2 | 0 | 0 | 0 | 0 |
| Folate+ | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 |
| MTHFR+ | 98.2 | 88.6 | 97.0 | 98.0 | 81.4 | 95.0 | 98.2 | 81.0 | 95.0 | 98.0 | 91.2 | 96.4 | 96.6 | 89.6 |
| X6 | 31.8 | 43.2 | 58.8 | 57.4 | 18.2 | 28.4 | 26.2 | 18.2 | 28.0 | 27.0 | 1.2 | 4.0 | 1.6 | 0.6 |
| X7 | 5.2 | 5.8 | 8.8 | 8.8 | 13.0 | 15.2 | 10.2 | 12.8 | 15.2 | 10.2 | 0 | 0.2 | 0 | 0 |
| X8 | 7.0 | 14.0 | 18.6 | 15.2 | 20.8 | 30.8 | 26.6 | 20.4 | 30.8 | 27.0 | 2.8 | 7.6 | 3.2 | 2.4 |
| X9 | 6.4 | 10.6 | 14.4 | 11.0 | 21 | 28.6 | 23.7 | 20.6 | 28.6 | 24.2 | 0 | 0 | 0 | 19.8 |
| X10 | 6.4 | 2.0 | 7.8 | 7.0 | 2.6 | 8.0 | 8.0 | 2.4 | 8.0 | 7.8 | 1.8 | 5.8 | 1.8 | 1.6 |
| X15 | 3.8 | 8.4 | 15.4 | 17.0 | 33.8 | 37.2 | 22.0 | 34.2 | 37.8 | 22.8 | 0.4 | 13.2 | 0.4 | 0.8 |
| Smoke* X15 | 2.0 | 0.2 | 2.8 | 3.6 | 8.8 | 16.4 | 14.4 | 7.2 | 16.2 | 14.6 | 0 | 28.8 | 0 | 1.0 |
| Alcoh* X15 | 2.0 | 0.2 | 4.4 | 4.8 | 1.6 | 6.2 | 6.6 | 1.4 | 6.2 | 6.8 | 1.6 | 20.4 | 1.6 | 2.4 |
| XPD* X15 | 3.2 | 0.4 | 4.2 | 5.2 | 1.6 | 6.0 | 7.4 | 1.0 | 5.8 | 7.4 | 2.4 | 18.0 | 2.4 | 2.6 |
| Fiber* X6 | 21.2 | 22.0 | 39.2 | 35.6 | 0 | 0.8 | 2.4 | 0 | 0.8 | 3.0 | 0 | 0 | 0 | 0 |
| Folate* X15 | 01.8 | 0.6 | 4.8 | 5.6 | 3.4 | 10.4 | 12.8 | 2.4 | 10.6 | 13.4 | 0.2 | 2.2 | 0.2 | 0.2 |
| Fiber* X15 | 5.6 | 1.6 | 6.2 | 7.0 | 0 | 0.2 | 1.6 | 0 | 0.2 | 18.0 | 0 | 0.2 | 0 | 0 |
| Folate* X7 | 5.0 | 1.0 | 5.4 | 5.6 | 0.2 | 0.1 | 1.8 | 1.0 | 1.0 | 1.8 | 0 | 0 | 0 | 0 |
| X7* X15+ | 93.6 | 99.2 | 100 | 99.8 | 3.6 | 17.2 | 40.8 | 3.2 | 17.0 | 41.6 | 99.8 | 100 | 100 | 99.8 |
| Avg. Correct Associations | 93.3 | 92.5 | 88.2 | 88.6 | 87.7 | 85.6 | 88.1 | 79.7 | 85.5 | 87.1 | 99.0 | 94.8 | 99.2 | 97.8 |
| Avg. Incorrect Associations | 6.7 | 7.5 | 11.9 | 11.4 | 12.3 | 14.4 | 11.9 | 20.3 | 14.4 | 12.9 | 1.0 | 5.2 | 0.7 | 2.18 |
| Avg. Ratio* | 13.9 | 12.4 | 7.4 | 7.8 | 7.1 | 5.9 | 7.4 | 3.9 | 5.9 | 6.8 | 99.0 | 18.2 | 136.0 | 44.9 |
+
denotes covariate in the true model
*
Avg. Ratio is calculated as the Avg. Correct Associations/Avg. Incorrect Associations