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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Mol Cancer Ther. 2010 Dec;9(12):3221–3232. doi: 10.1158/1535-7163.MCT-10-0570

Figure 2. PPAR- γ ligands inhibit EMT-induced migration, invasion and protease secretion.

Figure 2

A549 cells were serum starved for 24 h, stimulated with TGF-ß (5 ng/ml) in the presence or absence of PPAR-γ ligands rosi or tro at indicated concentrations. After 72 h, Conditioned media was collected to assess protease secretion by gelatin zymography (B) and cells were trypsinized and plated in uncoated or matrigel coated transwell chambers to assess cellular migration and invasion respectively (A). Error bars represent the standard error mean (SEM) from three independent experiments.