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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: J Immunol. 2010 Nov 17;186(1):143–155. doi: 10.4049/jimmunol.1000290

Figure 2. Increased Treg cells, and altered CD44 and CD43 expression profiles on peripheral CD8 and CD4 T cells in T-TRAF3−/− mice.

Figure 2

(A) Representative FACS profiles of splenocytes from LMC and T-TRAF3−/− mice stained for CD4, CD25 and Foxp3 expression. (B) Percentages and numbers of CD4 (CD4+CD8−CD25−), CD8 (CD4− CD8+), and Treg (CD4+CD25+Foxp3+) cells in spleens and LN of LMC and T-TRAF3−/− mice. Data shown are results of four independent experiments (mean ± SEM). (C) Representative FACS profiles of CD44 expression on CD8+ or CD4+ T cells in spleens, LN, and thymus of LMC (solid profile) and T-TRAF3−/− (dashed profile) mice. (D) Representative FACS profiles of CD43 expression on CD8+ or CD4+ T cells in spleens, LN, and thymus of LMC (solid profile) and T-TRAF3−/− (dashed profile) mice. Mice analyzed were 8 to 12 weeks old.

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