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. Author manuscript; available in PMC: 2011 Feb 24.
Published in final edited form as: Oncogene. 2010 Nov 8;30(6):751–756. doi: 10.1038/onc.2010.480

Figure 4. Transient suppression of Dnmt1 protects against radiation-induced genomic instability.

Figure 4

a, Doxycycline-dependent repression of Dnmt1 in mouse ES cells assessed by Western blot. b, SCEs in primary bystanders to normal and Dnmt1 transiently-deficient cells. c, SCEs in naive (secondary bystander) cells exposed to media from primary bystanders to normal and Dnmt1 transiently-deficient cells. Data analysis as per caption for Fig. 2.