Table 1. Multivariate analysis of risk factors for progression to acute lung injury in patients with evidence of existing lung injury on chest radiograph.
Risk factor | OR | 95% CI | p-value |
---|---|---|---|
>2 l/min supplemental O2† | 8.1 | 2.7–24.5 | 0.0002 |
Modified REMS (per 1 point increase) | 1.2 | 1.0–1.4 | 0.07 |
Immunosuppression‡ | 2.6 | 0.9–7.4 | 0.07 |
Airspace opacity beyond bases§ | 1.3 | 0.4–3.8 | 0.68 |
SIRS | 0.9 | 0.2–4.0 | 0.88 |
>2 l/min nasal cannula: amount of supplemental oxygen required to maintain an oxygen saturation >90%.
Immunosuppression: active immunosuppression as defined by APACHE II.
Airspace opacity beyond bases: airspace opacities on chest radiograph beyond bases compared with bibasilar opacities or diffuse interstitial edema.
APACHE II: Acute Physiologic and Chronic Health Evaluation II; OR: Odds ratio; REMS: Rapid Emergency Medicine Score; SIRS: Systemic inflammatory response syndrome.
Reprinted from [40] with permission of the American College of Chest Physicians.