. Author manuscript; available in PMC: 2011 Oct 1.

Published in final edited form as: Expert Rev Respir Med. 2010 Dec;4(6):785–797. doi: 10.1586/ers.10.78

Table 1. Multivariate analysis of risk factors for progression to acute lung injury in patients with evidence of existing lung injury on chest radiograph.

Risk factor	OR	95% CI	p-value
>2 l/min supplemental O₂^†	8.1	2.7–24.5	0.0002
Modified REMS (per 1 point increase)	1.2	1.0–1.4	0.07
Immunosuppression^‡	2.6	0.9–7.4	0.07
Airspace opacity beyond bases^§	1.3	0.4–3.8	0.68
SIRS	0.9	0.2–4.0	0.88

^†

>2 l/min nasal cannula: amount of supplemental oxygen required to maintain an oxygen saturation >90%.

^‡

Immunosuppression: active immunosuppression as defined by APACHE II.

^§

Airspace opacity beyond bases: airspace opacities on chest radiograph beyond bases compared with bibasilar opacities or diffuse interstitial edema.

APACHE II: Acute Physiologic and Chronic Health Evaluation II; OR: Odds ratio; REMS: Rapid Emergency Medicine Score; SIRS: Systemic inflammatory response syndrome.

Reprinted from [40] with permission of the American College of Chest Physicians.