Table 3.
Group | LV muscle area (mm2) | Scar area (mm2) | IVS thickness (mm) | Capillary density (count/mm2) |
C | 53.6±4.6 | 12.8±5.2 | 1.8±0.4 | 150.3±50.0 |
ET | 60.6±15.0 | 4.1±2.6‡ | 2.8±1.0§ | 146.6±38.9 |
M | 64.2±8.1 | 8.2±3.1 | 2.2±0.6 | 168.1±50.7 |
IR | 65.9±11.7 | 8.1±2.0 | 2.2±0.4 | 196.1±22.0 |
M+N | 62.0±3.3 | 13.7±5.4 | 2.2±0.2 | 135.4±43.0 |
ET+M | 65.4±11.0 | 7.5±3.2 | 3.1±0.4¶| | 136.2±46.9 |
ET+N | 85.1±5.7* | 31.5±11.5† | 2.8±0.4 | 145.3±22.3 |
Results are shown as mean±SD.
p<0.05 vs. all other groups;
p = 0.0001 vs. all other groups;
p = 0.01 vs. C and vs. M+N;
p<0.05 vs C.
p<0.05 vs C, M and IR.
LV = left ventricular; IVS = interventricular septum; C = control; ET = exercise training; M = morphine; IR = intermittent ischemia-reperfusion; M+N = morphine plus naloxone; ET+M = exercise training plus morphine; ET+N = exercise training plus naloxone.