Table 3.
Characteristics | rFVIIa Alive at 24 h (n = 48) | rFVIIa Dead at 24 h (n = 24) | p‐Value |
Age | 38 (±16) | 38 (±20) | 0.96 |
ISS | 44 (±14) | 42 (±16) | 0.49 |
Head AIS* | 2 (0‐5)* | 0.5 (0‐5)* | 0.42 |
Hemoglobin (g/L) | 101 (±30) | 92 (±23) | 0.22 |
Platelet count (× 104) | 190 (±101) | 127 (±81) | 0.0096 |
ipH | 7.3 (±0.1) | 7.1 (±0.2) | 0.0002 |
Base deficit | 8.0 (±5.3) | 14 (±7.3) | 0.0004 |
Fibrinogen (g/L) | 0.89 (±0.5) | 0.79 (±0.4) | 0.50 |
INR* | 1.34 (1.2‐1.9)* | 1.51 (1.3‐1.9)* | 0.06 |
Doses N (%) | |||
1 | 32 (66.7) | 20 (83.3) | |
2 | 14 (29.2) | 3 (12.5) | 0.22 |
3 | 2 (4.2) | 1 (4.2) | |
Time to first dose* (h) | 5.25 (3.2‐9.1) | 3.5 (2.1‐5.1) | 0.0089 |
Total dosage* | 89 (80‐147)* | 71.3 (65‐118)* | 0.08 |
Transfusion rate pre‐rFVIIa (RBC units/h) | 2.7 (±1.6) | 4 (±1.7) | 0.002 |
Mean (± standard deviation) and t‐test used.