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. 2011 Jan;66(1):101–106. doi: 10.1590/S1807-59322011000100018

Table 3.

Subgroup analysis of patients receiving rFVIIa.

Characteristics rFVIIa Alive at 24 h (n = 48) rFVIIa Dead at 24 h (n = 24) p‐Value
Age 38 (±16) 38 (±20) 0.96
ISS 44 (±14) 42 (±16) 0.49
Head AIS* 2 (0‐5)* 0.5 (0‐5)* 0.42
Hemoglobin (g/L) 101 (±30) 92 (±23) 0.22
Platelet count (× 104) 190 (±101) 127 (±81) 0.0096
ipH 7.3 (±0.1) 7.1 (±0.2) 0.0002
Base deficit 8.0 (±5.3) 14 (±7.3) 0.0004
Fibrinogen (g/L) 0.89 (±0.5) 0.79 (±0.4) 0.50
INR* 1.34 (1.2‐1.9)* 1.51 (1.3‐1.9)* 0.06
Doses N (%)
 1 32 (66.7) 20 (83.3)
 2 14 (29.2) 3 (12.5) 0.22
 3 2 (4.2) 1 (4.2)
Time to first dose* (h) 5.25 (3.2‐9.1) 3.5 (2.1‐5.1) 0.0089
Total dosage* 89 (80‐147)* 71.3 (65‐118)* 0.08
Transfusion rate pre‐rFVIIa (RBC units/h) 2.7 (±1.6) 4 (±1.7) 0.002

Mean (± standard deviation) and t‐test used.