Figure 2. A comparison of the α₄β₇-reactivities mediated by the V1/V2 regions of a month-1 gp120 and month 41 gp120 isolated from a single patient.

A) The gp120 V1/V2 sequences from patient QA203 obtained at month 1 and month 41 are listed. PNGs are highlighted in red. Variants, 1, 2 and 3 of QA203M41 are included with the N/Q substitutions highlighted in red. B) α₄β₇-reactivities of chimeric gp120s encoding the V1/V2 regions of QA203M1, QA203M41 and QA203M41 variant 1 are reported as mean fluorescence intensity. C) A comparison of the α₄β₇-reactivities of variants 1, 2 and 3 of QA203M41. QA203M41 is included for reference. Error bars represent the standard deviation of two replicates, and results are representative of three independent experiments using independent donor CD4⁺ T cells.