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. 2011 Feb 24;7(2):e1001301. doi: 10.1371/journal.ppat.1001301

Figure 4. Effect of glycan content on the α4β7-reactivity.

Figure 4

A) α4β7-reactivity of the ancestral AN1 gp120 (subtype B) produced in CHO-S cells, 293F cells, CHO lec1 cells and kifunensine treated 293F cells, were compared and reported as mean fluorescence intensity (MFI). AN1 V1/V2 PNGΔs were also included. Results are representative of three independent experiments using independent donor CD4+ T cells. B) Positions of all PNGs and the α4β7 binding site in the V1/V2 loop of AN1 gp120 are illustrated.

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