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. 2011 Feb 24;7(2):e1001301. doi: 10.1371/journal.ppat.1001301

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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A) Levels of CD4-reactivity (red) and α₄β₇-reactivity (blue) were assessed for each patient 205F gp120, B) the QA203 month 1 and month 41 chimeric gp120s, C) w.t. and N144Q 92Ug037 gp120s, D) the 1-month and 12 month CAP88 gp120s and a panel of well characterized gp120s including an ancestral B (AN1) and an ancestral C (ANC1) gp120. Inset indicates the staining of the cells employed in this assay with PE conjugated CD4 (red) and β7 (blue) mAbs. Error bars represent the standard deviation of two replicates, and results are representative of three independent experiments using independent donor CD4⁺ T cells.

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