Skip to main content
. 2011 Feb 24;6(2):e16408. doi: 10.1371/journal.pone.0016408

Table 1. Statistical analysis of relapse in diffuse large B cell lymphoma patients whose miR-92a levels were determined at complete response phase.

univariate multivariate
Factors at diagnosis No. (n = 34*) Relpased (n = 6) P value odds ratio 95% CI P value Corrected odds ratio 95% CI
Sex
male 13 1 .231 0.267 0.02743 to 2.592 .833 1.3037 0.066 to 8.971
female 21 5
Age
≥60 years 20 4 1 1.5 0.2346 to 9.593 .50 0.418 0.03 to 5.287
<60 years 14 2
LDH
Elevated 16 4 .289 2.667 0.4170 to 17.05 .673 1.625 0.170 to 15.522
Normal 18 2
B symptoms
Yes 16 3 .874 1.154 0.1976 to 6.738 .853 0.730 0.026 to 20.544
No 18 3
Clinical stage
III+IV 18 5 .18 5.769 0.5946 to 55.98 .062 23.189 0.858 to 629.583
I+II 16 1
International Prognostic Index
high + high-int 14 3 .628 1.545 0.2629 to 9.085 .972 0.943 0.038 to 23.744
low + low int 20 3
Plasma miR-92a
Low (<0.2165) 12 5 .007 15 1.486 to 151.4 .020 16.232 1.562 to 168.725
Normal (≥0.2165) 22 1

Abbreviations: CI, confidence interval; LDH, lactate dehydrogenase.

*Patients who had been followed for more than 6 months and who did not receive any hematopoietic stem cell transplantation were analyzed.