Table 2. Statistical analysis of relapse in follicular lymphoma patients whose miR-92a levels were determined at complete response and complete response uncertain phase.
| univariate | |||||
| Factors at diagnosis | No. (n = 19) | Relpased (n = 6) | P value | odds ratio | 95% CI |
| Sex | |||||
| male | 10 | 3 | .876 | 0.857 | 0.1235 to 5.947 |
| female | 9 | 3 | |||
| Age | |||||
| ≥60 years | 9 | 4 | .252 | 3.2 | 0.4192 to 24.43 |
| <60 years | 10 | 2 | |||
| LDH | |||||
| Elevated | 2 | 0 | .31 | 0.354 | 0.01463 to 8.559 |
| Normal | 17 | 6 | |||
| Hemoglobin | |||||
| ≤120 g/L | 3 | 2 | .154 | 6 | 0.4220 to 85.30 |
| ≥120 g/L | 16 | 4 | |||
| Ann Arbor stage | |||||
| III+IV | 13 | 5 | .342 | 3.125 | 0.2776 to 35.18 |
| I+II | 6 | 1 | |||
| No. of nodal area involved | |||||
| >4 | 6 | 2 | .911 | 1.125 | 0.1425 to 8.884 |
| ≤4 | 13 | 4 | |||
| Bone marrow invasion | |||||
| Yes | 8 | 3 | .636 | 1.6 | 0.2271 to 11.27 |
| No | 11 | 3 | |||
| β2-microglobulin elevation* | |||||
| Yes | 8 | 3 | .41 | 2.4 | 0.2910 to 19.79 |
| No | 10 | 2 | |||
| FLIPI | |||||
| High | 3 | 1 | |||
| Intermediate | 8 | 3 | .863 | ||
| Low | 8 | 2 | |||
| FLIPI-2* | |||||
| High | 4 | 3 | |||
| Intermediate | 11 | 2 | .047 | ||
| Low | 3 | 0 | |||
| Plasma miR-92a | |||||
| Low (<0.2165) | 8 | 5 | .013 | 16.67 | 1.361 to 204.2 |
| Normal (≥0.2165) | 11 | 1 |
Abbreviations: CI, confidence interval; LDH, lactate dehydrogenase; FLIPI, Follicular Lymphoma International Prognostic Index.
*Data from 1 patient were missing.