Table 1. Function enrichment of the subnetwork genes.

Diseases and disorders	P-valuea	#molecules
CNV-subnetwork
Neurological disease	9.41×10−11–3.56×10−5	132
Cancer	2.22×10−10–5.70×10−5	102
Genetic disorder	1.23×10−9–7.60×10−6	176
Psychological disorders	1.23×10−9–3.24×10−5	57
Reproductive system disease	2.22×10−9–4.78×10−5	49
HuGE-subnetwork
Neurological disease	2.02×10−52–5.62×10−7	143
Genetic disorder	4.47×10−37–5.15×10−7	165
Psychological disorders	4.34×10−27–4.79×10−7	81
Skeletal and muscular disorders	1.54×10−25–5.15×10−7	112
Organismal injury and abnormalities	9.49×10−20–5.92×10−7	54

^a P-values were calculated by Fisher's exact test, indicating probability of the association of the candidate genes with the canonical pathway from chance. Each disease category has several pathways, thus, the range of their P-values is provided.