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. 2011 Feb 24;6(2):e17142. doi: 10.1371/journal.pone.0017142

Table 3. Associations between selected SNPs and Gleason grade and Stage.

Odds Ratio1 (95% CI) Odds Ratio1 (95% CI)
SNP Gleason <8 Gleason 8–10 P case-only test Stage AB StageCD P case-only test
rs721048 1.13 (1.07–1.20) 1.07 (0.96–1.19) 0.30 1.13 (1.07–1.20) 1.09 (0.99–1.19) 0.5
rs1465618 1.10 (1.05–1.16) 1.17 (1.06–1.30) 0.15 1.13 (1.07–1.19) 1.07 (0.97–1.17) 0.34
rs12621278 0.87 (0.79–0.96) 0.77 (0.62–0.95) 0.27 0.87 (0.78–0.96) 0.85 (0.71–1.02) 0.86
rs2660753 1.10 (1.03–1.18) 1.11 (0.98–1.26) 0.81 1.13 (1.05–1.21) 1.14 (1.01–1.27) 0.82
rs4857841 1.13 (1.07–1.18) 1.15 (1.05–1.26) 0.54 1.14 (1.09–1.20) 1.15 (1.06–1.25) 0.53
rs17021918 0.91 (0.87–0.95) 0.96 (0.88–1.05) 0.22 0.89 (0.58–0.93) 1.01 (0.93–1.09) 0.004
rs12500426 1.07 (1.03–1.12) 0.99 (0.91–1.08) 0.09 1.08 (1.04–1.13) 0.97 (0.89–1.04) 0.007
rs7679673 0.88 (0.84–0.92) 0.86 (0.79–0.94) 0.63 0.88 (0.84–0.92) 0.85 (0.78–0.92) 0.49
rs9364554 1.10 (1.05–1.15) 1.03 (0.94–1.13) 0.28 1.07 (1.02–1.12) 1.13 (1.04–1.22) 0.30
rs10486567 0.83 (0.78–0.88) 0.93 (0.83–1.05) 0.06 0.81 (0.77–0.85) 0.91 (0.84–1.00) 0.02
rs6465657 1.10 (1.05–1.15) 1.09 (1.01–1.18) 0.80 1.12 (1.07–1.17) 1.03 (0.96–1.11) 0.02
rs1512268 1.11 (1.06–1.16) 1.02 (0.94–1.11) 0.08 1.12 (1.07–1.17) 1.05 (0.97–1.13) 0.05
rs2928679 1.07 (1.03–1.12) 1.09 (1.00–1.19) 0.81 1.08 (1.03–1.12) 1.05 (0.97–1.14) 0.78
rs4961199 1.10 (1.04–1.17) 1.08 (0.97–1.22) 0.82 1.08 (1.01–1.15) 1.10 (0.99–1.22) 0.70
rs1016343 1.24 (1.17–1.31) 1.31 (1.18–1.45) 0.33 1.26 (1.19–1.33) 1.25 (1.15–1.37) 0.92
rs7841060 1.23 (1.17–1.30) 1.31 (1.18–1.45) 0.32 1.26 (1.19–1.33) 1.24 (1.13–1.36) 0.82
rs16901979 1.43 (1.27–1.60) 1.39 (1.12–1.72) 0.91 1.40 (1.24–1.58) 1.55 (1.29–1.86) 0.33
rs620861 0.85 (0.81–0.89) 0.89 (0.81–0.97) 0.34 0.87 (0.83–0.91) 0.82 (0.75–0.89) 0.37
rs6983267 0.80 (0.77–0.84) 0.84 (0.77–0.91) 0.62 0.82 (0.78–0.85) 0.82 (0.76–0.89) 0.54
rs1447295 1.41 (1.32–1.51) 1.31 (1.16–1.49) 0.35 1.36 (1.27–1.46) 1.51 (1.36–1.68) 0.06
rs4242382 1.43 (1.34–1.53) 1.38 (1.22–1.55) 0.73 1.39 (1.30–1.49) 1.49 (1.34–1.66) 0.24
rs7837688 1.39 (1.30–1.49) 1.33 (1.18–1.51) 0.72 1.34 (1.25–1.44) 1.47 (1.32–1.64) 0.09
rs16902094 1.19 (1.12–1.27) 1.07 (0.94–1.21) 0.08 1.18 (1.10–1.26) 1.18 (1.06–1.31) 0.74
rs1571801 1.07 (1.02–1.13) 1.10 (1.01–1.21) 0.50 1.07 (1.02–1.13) 1.09 (1.00–1.19) 0.62
rs10993994 1.23 (1.18–1.29) 1.21 (1.12–1.32) 0.94 1.25 (1.19–1.30) 1.20 (1.11–1.29) 0.29
rs4962416 1.10 (1.05–1.16) 1.09 (1.00–1.20) 0.93 1.10 (1.05–1.15) 1.10 (1.01–1.19) 0.88
rs7127900 1.14 (1.08–1.21) 1.05 (0.95–1.17) 0.14 1.14 (1.08–1.20) 1.16 (1.06–1.28) 0.81
rs12418451 1.11 (1.06–1.17) 1.20 (1.10–1.31) 0.09 1.14 (1.08–1.19) 1.06 (0.97–1.15) 0.14
rs7931342 0.86 (0.82–0.90) 0.81 (0.75–0.88) 0.21 0.85 (0.81–0.89) 0.88 (0.81–0.94) 0.33
rs10896449 0.85 (0.82–0.89) 0.80 (0.74–0.87) 0.13 0.84 (0.80–0.87) 0.86 (0.80–0.93) 0.34
rs11649743 0.88 (0.83–0.93) 0.93 (0.84–1.03) 0.40 0.89 (0.84–0.94) 0.84 (0.76–0.93) 0.21
rs4430796 0.78 (0.75–0.81) 0.84 (0.77–0.91) 0.05 0.81 (0.77–0.84) 0.78 (0.73–0.85) 0.47
rs7501939 0.81 (0.77–0.85) 0.85 (0.77–0.92) 0.30 0.83 (0.80–0.87) 0.80 (0.74–0.86) 0.28
rs1859962 1.20 (1.15–1.25) 1.17 (1.08–1.27) 0.70 1.18 (1.13–1.24) 1.22 (1.13–1.31) 0.58
rs266849 0.91 (0.86–0.96) 1.10 (1.00–1.22) 0.0004 0.92 (0.87–0.97) 0.98 (0.89–1.08) 0.18
rs2735839 0.84 (0.79–0.89) 1.07 (0.95–1.19) 0.0001 0.85 (0.80–0.91) 0.92 (0.83–1.03) 0.17
rs5759167 0.87 (0.83–0.91) 0.85 (0.78–0.93) 0.59 0.88 (0.84–0.92) 0.82 (0.76–0.89) 0.11
rs5945572 1.24 (1.16–1.32) 1.20 (1.06–1.36) 0.56 1.22 (1.14–1.31) 1.27 (1.14–1.42) 0.57
rs5945619 1.26 (1.19–1.34) 1.19 (1.05–1.34) 0.26 1.22 (1.14–1.30) 1.33 (1.20–1.28) 0.16
1

Odds ratios were estimated using multinomial regression.