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. 2011 Feb 24;7(2):e1001092. doi: 10.1371/journal.pcbi.1001092

Figure 1. Monochromatic analysis overview.

Figure 1

We evaluate the monochromatic nature of biological processes (Within) and of the connections between processes (Between). Circles represent processes and links between them represent the set of SGA genetic interactions that connect genes within the processes. The color represents the monochromatic nature of the processes and connections (green is monochromatic positive, red is monochromatic negative, grey is non-monochromatic). We first define the processes and their connections and then evaluate their monochromatic nature. In the third step we remove various features, such as genes whose products are part of a complex and finally analyze the resulting change in monochromatic nature of the processes and connections.