Table 1.

Review Inclusion Criteria

Published in English Published in a peer-reviewed journal Published in the past 25 years (1984–2009) Randomized controlled trial Patients must have spinal osteoarthritis / osteoarthrosis / degenerative joint disease and/or degenerative disc disease proven via diagnostic imaging Use glucosamine sulfate (or glucosamine HCl) and/or chondroitin sulfate and/or methylsulfonylmethane (MSM) Use of other medications, supplements, or interventions tolerable Comparison group could consist of a do nothing control, placebo, or a different active treatment Outcome measures include an assessment of pain and/or disability due to pain