Table 2.

Significant grey matter differences between groups

Region	Cluster size	x	y	z	zmax
Healthy controls > PFX+
Left and right cerebellar hemispheres, vermis, ventral medial temporal regions	53025	5	−77	−21	6.43
Cingulate cortex, dorsomedial prefrontal cortex, pre-SMA, SMA, precuneus	22729	−1	40	29	5.95
Left insula/frontal operculum	4663	−57	10	1	5.38
Left orbital frontal cortex	4228	−18	62	−19	6.78
Left and right cerebellar lobule IX	3558	−8	−45	−58	5.45
Right insula	2938	41	−6	3	5.75
Thalamus	2076	−2	−19	13	5.69
Left inferior frontal cortex	1876	−51	10	29	5.57
Right orbital frontal cortex	1656	21	65	−16	6.26
Left dorsolateral prefrontal cortex	1213	−33	54	23	4.98
Right superior frontal cortex	743	31	11	62	5.14
	686	23	37	51	5.35
Bilateral gyrus rectus	559	3	29	−29	4.80
Left superior parietal cortex	553	−28	−77	47	5.22
Right superior parietal cortex	341	35	−69	53	4.77
Right premotor cortex	200	59	−5	39	5.08
Left angular gyrus	190	−55	−60	41	4.98
Right angular gyrus	173	62	−58	37	4.75
Left superior frontal cortex	159	−32	4	60	4.81
Left post-central gyrus	148	−61	−24	41	4.73
PFX+ > Healthy controls
Left superior/middle temporal gyrus	3674	−46	−50	0	5.92
	275	−48	−9	−22	4.78
Right middle temporal gyrus	1560	52	−47	−12	5.40
	239	49	−50	10	4.77
Left lateral occipital gyrus	204	−29	−85	−2	4.74
	135	−33	−73	14	4.74
Left medial orbital gyrus	185	−20	26	−11	4.71
Right middle frontal gyrus	101	30	42	12	4.72
PFX− > PFX+
Cerebellar lobules V/VI/VII	5072	5	−78	−22	5.27
Right cerebellar hemisphere VI	1613	30	−23	−36	5.10
Dorsal anterior cingulate/paracingulate	1471	6	30	40	4.65
Left cerebellar hemisphere VIIB/Crus I	841	−48	−53	−47	4.41
Thalamus	625	−4	−18	12	4.30
Right precuneus	355	6	−60	60	4.66
Right dorsomedial prefrontal cortex	257	16	51	42	4.54
Left cerebellar hemisphere Crus I	222	−22	−90	−27	4.20
Left frontal pole	191	−15	69	6	4.12
Right superior frontal cortex	174	33	47	33	4.51
Left premotor cortex	168	−52	6	40	4.34
Left superior frontal cortex	146	−34	4	59	4.61
Left posterior cingulate cortex	135	−5	−31	47	4.08
PFX+ > PFX−
No significant clusters
Healthy controls > PFX−
No significant clusters
PFX− > Healthy controls
No significant clusters

SMA = supplementary motor area.