Figure 3.

The frequency range of NMDA-induced firing. A, Comparison of dIN firing frequency distributions evoked by NMDA and glutamate applications in the presence of 1 μm strychnine, 20 μm SR95531, 2 μm DHβe, 5 μm NBQX, and 150–200 μm Cd²⁺ (NMDA, 1192 spikes from 7 dINs; glutamate, 680 spikes from 5 dINs). Counts of spikes per frequency bin were normalized to percentages for each neuron and averaged across the sample. B, C, Effects of current level on neuronal firing in the presence of NMDA in dINs (red symbols and lines in B) and non-dINs (blue in C). The gray symbols in C show non-dIN firing in control saline. The green area shows normal swim frequency range (10–25 Hz).