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. Author manuscript; available in PMC: 2011 Feb 25.
Published in final edited form as: NMR Biomed. 2008 Aug;21(7):704–712. doi: 10.1002/nbm.1244

Figure 5. Differentiation of lacZ- and WT-breast tumors in vivo.

Figure 5

19F NMR spectra (188 MHz) of a mouse bearing two thigh tumors. Following intratumoral injection of an aqueous DMSO solution of PFONPG (50 μl) in wild type (WT) tumor and OFPNPG (50 μl) in lacZ transfected tumor, complete conversion of OFPNPG was seen in 30 min, while no conversion of PFONPG was observed. Each spectrum was acquired in 5 mins and 60 Hz exponential line broadening was applied.