FIGURE 8.
Effect of selected verteporfin analogs on chloroquine-induced autophagosome accumulation. A, structures of protoporphyrin IX, verteporfin, and benzopophyrin derivatives. B, MCF-7 EGFP-LC3 cells were incubated for 4 h in complete medium with different concentrations of each verteporfin analog in the presence of 75 μm chloroquine. Punctate EGFP-LC3 was quantitated using the automated microscopy assay (mean ± S.D. (error bars), n = 3).