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. 2010 Dec 29;286(9):7301–7307. doi: 10.1074/jbc.M110.203315

FIGURE 4.

FIGURE 4.

Stereo view of the water-mediated hydrogen bonds on the right- and left-hand sides of the prosequence of the MTGase zymogen in the active cleft. The criterion that we used for the presence of a hydrogen bond is that the distance between the donor and acceptor had to be ≤3.3 Å. The side chains of those residues that formed hydrogen bonds by using the main chain amide nitrogen or oxygen atom, such as Leu-18 and Glu-31, have not been shown.