. Author manuscript; available in PMC: 2012 Jan 1.

Published in final edited form as: Ann Neurol. 2011 Jan;69(1):181–192. doi: 10.1002/ana.22248

TABLE 1.

Demographics

Characteristic	HC	MCI	DAT
Clinical follow-up, No.	106	65	35
Age at baseline, yr	73.1±7.5	73.4±8.5	71.7±8.9

Gender, M/F	54/52	36/29	19/16
Years of education	13.2±3.5	12.2±4.3	11.9±3.4

MMSE at baseline	29.2±1.0	26.5±2.9^a	22.5±3.7^a

CDR at baseline	0.07±0.17	0.47±0.17^a	0.93±0.35^a
CDR SOB at baseline	0.16±0.41	1.56±1.11^a	4.53±2.15^a

%ApoE ε4	33%	63%^b	71%^b
Repeat PiB PET scan, No.	104	48	33

Time PET₂ – PET₁, mo	20±3	20±3	20±5

Significantly different from HC (p < 0.05).

Significantly different from HC (Fisher exact test p < 0.01).

HC = healthy control; MCI = mild cognitive impairment; DAT = dementia of the Alzheimer type; MMSE = Mini mental state examination; CDR = Clinical Dementia Rating; SOB = sum of boxes; ApoE = apolipoprotein E; PiB = [¹¹C]Pittsburgh compound B; PET = positron emission tomography.