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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Ann Neurol. 2011 Jan;69(1):181–192. doi: 10.1002/ana.22248

TABLE 4.

Changes in PiB SUVR in Subjects with High PiB Retention at Baseline Who Completed the 38-Month Follow-up

Measure HC MCI DAT
No. 10 7 10

Baseline 1.89±0.27 2.56±0.46 2.40±0.29
20-month follow-up 1.93±0.31 2.61±0.50 2.50±0.29

38-month follow-up 2.06±0.28 2.74±0.49 2.50±0.29

ΔSUVR20-B 0.04 0.05 0.10
 Δ% 2.1% 1.9% 4.2%

p NS NS 0.03
ΔSUVR38-B 0.17 0.18 0.10

 Δ% 8.9% 7.0% 4.2%

p 0.001 0.0009 0.05

ΔSUVR38-20 0.13 0.13 0.00

 Δ% 6.7% 5.0% 0.0%
p 0.009 NS NS

PiB = [11C]Pittsburgh compound B; SUVR = standardized uptake value ratio; HC = healthy control; MCI = mild cognitive impairment; DAT = dementia of the Alzheimer type; NS = not significant.