Table 3.
Performance Characteristics with the TRUstart Algorithm in the First 10 h and Successive Time and Comparison of the TRUstart Algorithm to the First-Generation Algorithma
| TRUstart first 10 h | TRUstart after 10 h | P valuesb | ||||||||||
| CG-EGA | Hypoc | Euc | Hyperc | All Data | Hypo | Eu | Hyper | All Data | Hypo | Eu | Hyper | All Data |
| Clinically accurate | 54.6 (54) | 94.6 (1425) | 93.3 (874) | 92.6 (2353) | 53.2 (108) | 96.2 (2968) | 95.4 (1926) | 94.2 (5002) | 0.222 | 0.004 | 0.050 | 0.016 |
| Benign errors | 9.1 (9) | 4.4 (66) | 3.3 (31) | 4.2 (106) | 5.9 (12) | 3.3 (102) | 3.0 (60) | 3.3 (174) | 0.187 | 0.016 | 0.310 | 0.058 |
| Clinical errors | 36.4 (36) | 1.0 (15) | 3.4 (32) | 3.3 (83) | 40.9 (83) | 0.6 (17) | 1.7 (34) | 2.5 (134) | 0.431 | 0.067 | 0.070 | 0.058 |
| Mean ARDd | 19.2 (99) | 13.9 (1506) | 10.7 (937) | 13.4 (2542) | 22.8 (203) | 16.3 (3087) | 10.4 (2020) | 14.9 (5310) | 0.248 | 0.437 | 0.027 | 0.267 |
| Median ARDd | 14.8 (99) | 10.7 (1506) | 8.3 (937) | 10.0 (2542) | 18.3 (203) | 12.4 (3087) | 8.4 (2020) | 10.9 (5310) | 0.936 | 0.761 | 0.044 | 0.443 |
| TRUstart calibrated after 10 h | First-generation algorithm after 10 h | P values | ||||||||||
| CG-EGA | Hypo | Eu | Hyper | All Data | Hypo | Eu | Hyper | All Data | Hypo | Eu | Hyper | All Data |
| Clinically accurate | 54.4 (105) | 96.4 (2895) | 95.7 (1889) | 94.6 (4889) | 46.0 (87) | 96.7 (2843) | 96.8 (1798) | 94.8 (4719) | 0.632 | 0.187 | 0.448 | 0.527 |
| Benign errors | 4.7 (9) | 3.1 (92) | 2.6 (51) | 2.9 (152) | 3.7 (7) | 2.8 (82) | 1.8 (34) | 2.5 (123) | 0.190 | 0.364 | 0.130 | 0.064 |
| Clinical errors | 40.9 (79) | 0.6 (17) | 1.7 (33) | 2.5 (129) | 50.3 (95) | 0.5 (14) | 1.4 (25) | 2.7 (134) | 0.368 | 0.323 | 0.740 | 0.527 |
| Mean ARD | 22.5 (193) | 16.4 (3004) | 10.4 (1973) | 14.9 (5170) | 25.4 (189) | 16.4 (2939) | 9.1 (1848) | 14.8 (4976) | 0.409 | 0.715 | 0.016 | 0.725 |
| Median ARD | 18.2 (193) | 12.4 (3004) | 8.3 (1973) | 10.9 (5170) | 22.7 (189) | 12.8 (2939) | 7.3 (1848) | 10.5 (4976) | 0.269 | 0.761 | 0.015 | 0.294 |
a
Table entries are % (n).
b
P values were determined by paired t test, and the Bonferroni correction was used to determine the significance level for multiple analyses of the same data set (p< .006).
c
Hypo, hypoglycemia (≤70 mg/dl); Eu, euglycemia (71–180 mg/dl); Hyper, hyperglycemia (>180 mg/dl)
d
In the hypoglycemic region, the absolute difference rather than the ARD is reported.