Table 2.
Baseline characteristics of children with MDR TB
| Age (m) | Sex | TB previous | TB contact | Baseline Clinical | HIV | ART at baseline (m) | CD4 # baseline | CD4% baseline | RNA PCR baseline | Time to appropriate treatment (m) | WAZ-score | Drug Resistance | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | F | No | No | αExprem, CLD | Neg | LTFU$ | -3.1 | MDR | ||||
| 2 | 3.4 | M | No | No | ααExprem, CDH,CLD, ASD | Neg | Died 3 days after investigation | -3.9 | MDR | ||||
| 3 | 3.8 | M | No | No | Well | Neg | 4.0 | -0.5 | MDR, Strep |
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| 4 | 5.2 | M | No | No | WHO IV Marasmus | Pos | 2 | 2.0 | -1.8 | MDR | |||
| 5 | 11.9 | M | No | No | Kwashiorkor | Neg | 3.3 | -3.0 | MDR | ||||
| 6 | 18.5 | M | No | Yes mom defaulted | Kwashiorkor | Neg | 4.5 | -2.0 | MDR, Strep |
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| 7 | 25 | M | No | Yes (father) | WHO IV Kwashiorkor | Pos | No (Defaulted) | 264 | 23.2 | 4.9 | 15 | -2.3 | MDR, Strep |
| 8 | 29.2 | F | No | Unk | UWFA | Neg | 3 | -3.2 | MDR Strep |
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| 9 | 62 | F | no | no | WHO IV | Pos | 1 | 381 | 23.2 | 6.3 | 0.8 | -3.5 | MDR |
| 10 | 83.7 | F | Yes 2001 and 2002 and 2008 ∞ | U | WHO IV CLD | Pos | 1st line 23 m. 2nd line regimen 4 m. Poor adherence | 105 | 5.1 | 1.4 | 0.3 | -3.5 | MDR, EMB, Strep |
| 11 | 96.7 | F | No | Yes | WHO IV | Pos | Yes 36 m Defaulter | 9 | 1.1 | 5.1 | 1.3 | -2.7 | MDR, Strep, EMB |
| 12 | 144 | F | Yes 2001, 2005, 2007 ^ | Yes mom demised from TB 2004 | WHO III | Pos | 11 m 1st line Poor adherence 2nd line regimen 15 months | 254 | 32 | 4.1 | 2.5 | -1.0 | MDR, EMB, Strep |
| 13 | 144 | M | No | U | WHO IV | Pos | 2 | 36 | 2.2 | 5.5 | 1.5 | -2.4 | MDR, Strep, Eth, EMB |
| Median | 24 | 180 | 14.2 | 5.19 | 2.5 | -2.8 | |||||||
α Ex-premature infant, CLD= chronic lung disease.
αα CHD=Congenital diaphragmatic hernia, ASD=Atrial septum defect.
$ LTFU= Lost to follow up
^ Resistant to ethambutol and isoniazid: treated with ethionamide and ciprofloxacin.
∞ Admitted to MDR-TB Hospital