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Effect of mannan inoculation on influenza virus infection in mice. (A) Mortality of mice infected with seasonal or pandemic 2009 viruses. Each mouse was intranasally inoculated with 20 μl of virus suspension (containing 0% or 1% mannan) under anesthesia. (B) The severity of infection in each mouse was scored according to the maximum loss of body weight (% of weight on day 0 after infection), and mice with the same score were summed together.
