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. 2011 Feb 25;6(2):e16580. doi: 10.1371/journal.pone.0016580

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Chakraborty et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Shows the general conservation patterns with highly conserved amino acids in 3D structure of the IRS family members. Amino acid conservation scores were classified into 9 levels. The color scale for residue conservation is indicated in the figure. (B) Backbone structures with highly conserved amino acids of IRS family members proteins.