Table 3. Genotyping information for the meta-analysis of the effect of the SNP at position 158590601 (N417Y) in all cohorts.

Study*	N AD cases	N controls	N417Y FrequencyCase	N417Y FrequencyControl	OR	95% CI	% Weight
Greece	347	369	0.016	0.004	3.994	1.105–14.439	42.14
UK	421	593	0.007	0.004	1.700	0.515–5.608	48.86
Other Western Europeans	145	141	0.003	0.004	0.979	0.061–15.807	9.00
D+L pooled OR					2.319	1.007–5.340	100.00

*The Greek samples comprise of the pooled sample individual genotyping results, with some additional individuals recruited in the same cohort. The UK and “Other Western European samples” are from the MRC cohort, and the Addneuromed study. The UK samples comprise of individuals recruited from centres in London and Cardiff, and the “Other Western Europeans” from centres in Italy, Poland, France and Finland (see methods and references for more details).