Table 3. Correlations between post-mortem measures of nigrostriatal damage and in vivo MRI measurements at wk 5.
Histology | ||
MRI | TH+ cells SNc | TH+ fibres STR |
VM volume | .839 ** | .884 ** |
STR volume | .749 ** | .835 ** |
CTX volume | .840 ** | .882 ** |
LV volume | −.676 * | −.771 ** |
M1 thickness | .751 ** | .841 ** |
S1BF thickness | .494 | .574 |
SN T2 SI | .576 | .602 |
*Correlation is significant at the 0.05 level,
**correlation is significant at the 0.01 level. (Abbreviations: VM, ventral midbrain; STR, corpus striatum; CTX, cortex; LV, lateral ventricle; M1, primary motor cortex, S1BF, primary somatosensory cortex barrel field; SN, substantia nigra; SI, signal intensity).