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. 2011 Feb 25;6(2):e16889. doi: 10.1371/journal.pone.0016889

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Guo et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The elephant IgH locus is localized to scaffold 57. The length is approximately 2,974 kb from the most 5′ V_H segment (V_H2-112p) to the most 3′γ segment. Filled bars: potentially functional V_H genes; open bars: V_H pseudogenes: open bars and V-p; thin bars: truncated V_H segments and V-t; D_H: diversity genes; J_H: joining genes; μ: IgM coding gene; δ: IgD remnant; and γ: IgG coding gene. V_H and D_H genes are numbered based on the families to which they belong and their positions in the locus. The number before the dash (V_Hn or D_Hn) indicates the family, while the number after dash represents the genomic position. J_H genes are numbered based on the order of their locations in the locus. Double slashes indicate gaps >10 kb. Alpha and epsilon genes are not displayed on the map, but this does not imply their absence in the elephant IgH locus.