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OPN-induced neuroprotection is blocked by integrin receptor analog. Rat pups were treated with GRGDSP (5 µmol/L, 1µl) 15 minutes before OPN treatment. TTC staining at 48h post HI revealed that OPN-induced neuroprotection is blocked by integrin receptor analog treatment (*P<0.05, vs. HI+OPN-0.1). Vertical bars indicate SEM. N=10 in HI+PBS group, n=11 in HI+OPN-0.1 group, n=7 in HI+OPN-0.1+GRGDSP group.
